Comment # 7 on bug 109456 from Alex Williamson

Can you test this QEMU patch that's already in qemu.git for 4.1:

https://git.qemu.org/?p=qemu.git;a=commitdiff;h=3412d8ec9810b819f8b79e8e0c6b87217c876e32

Alternatively, setting the pci-hole64-size=0 can also avoid this issue:

 -global i440FX-pcihost.pci-hole64-size=0

or

 -global q35-host.pci-hole64-size=0

depending on your VM machine type.