I can't say for sure when this behavior changed where I cannot toggle quick setting option for WireGuard when the phone is locked. 

I know this was working in December so not sure if the December update for Android changed something or if this was an explicit change in the Android app. 

Wanted to see if any one else is seeing similar behavior and if there is anything that can be done about it?

I was using Tasker to automate toggling the quick setting when ever I was not connected to a specific WiFi network. That automation no longer works because I need to unlock the phone before that setting can be toggled.